This department operates 18 hours a day, six days a week, including holidays, and is responsible for ensuring all required screening and supplemental testing is completed for approximately 95,000 allogeneic, autologous and apheresis donations collected at Hoxworth Blood Center.
The department also ensures any potentially infectious or sub-standard product is quarantined and discarded to prevent release to general inventory.
Hoxworth Blood Center no longer performs required donor testing on site. QualTex Laboratories serves as the testing facility for Hoxworth Blood Center and has done so since 2015.
Current Food and Drug Administration (FDA) and AABB required testing, in addition to other supplemental testing is performed to detect/determine:
Infectious Disease Testing Information
The Donor Testing Laboratory receives many questions concerning the dates of infectious disease testing. The following table is a brief synopsis on the history and current status of infectious disease testing performed at Hoxworth Blood Center.
|INFECTIOUS DISEASE TESTING||DATE TEST FIRST IMPLEMENTED||CURRENT TESTING IMPLEMENTATION|
|Hepatitis B Surface Antigen (HBS)||Early 1970's||Abbott PRISM HBS 9/21/2006|
|Human Immuno deficiency Virus (HIV) Type 1 Antibody
||5/1/1985||Abbott PRISM HIV O Plus (Types 1&2, O, M) 12/1/2009|
|Hepatitis B Core Antibody (HBC)||7/1/1986||Abbott PRISM HBC 9/21/2006|
|Alanine Aminotransferase (ALT) Testing||10/14/1986||Discontinued 10/1/2004|
|Human T-Lymphotrophic Virus (HTLV) Type I Antibody
||3/1/1989||Abbott PRISM HTLV Types I/II
|Hepatitis C Virus (HCV) Antibody
||5/6/1990||Abbott PRISM HCV 9/11/2007|
|HIV p24 Antigen Testing by EIA||4/29/1996||Discontinued 6/1/2003|
|HCV by NAT||4/28/1999||HIV/HCV NAT combined in one assay 6/1/2003. Discontinued 5/2/11
|HIV by NAT||1/3/2000|
|HBV by NAT||5/2/11||HIV/HCV/HBV combined in one assay 5/2/11|
|West Nile Virus (WNV) by NAT||7/1/2003
(under IND protocol)
|Licensed test implemented 4/1/2006|
|Zika by NAT||10/13/16 (under IND protocol)|
||1960's||Antibody to T. pallidium in 1/31/1991|
||12/1/2007||Abbott PRISM Chagas
EIA = Enzyme Immunoassay
PRISM = Chemiluminescence Immunoassay
NAT = Nucleic Acid Testing
This laboratory also performed over 50,000 discrete Quality Control (QC) tests on randomly selected products. By testing randomly selected products, Hoxworth Blood Center is able to ensure that products meet the minimum quality assurance specifications set by the FDA and AABB. The result is that physicians can better manage blood transfusion therapy for their patients knowing that a standard minimum dose is available for transfusion.
Daily operations are managed by Jody Hupp, MLT(ASCP), Asst. Director. The Donor Testing Laboratory is under the direction of the Division and Medical Director Patricia Carey, MD.