Hoxworth

Quality Control Laboratory

The Quality Control Laboratory department operates 16 hours a day, seven days a week, including holidays, and is responsible for ensuring all required screening and supplemental testing is completed for approximately 95,000 allogeneic, autologous and apheresis donations collected at Hoxworth Blood Center.

The department also ensures any potentially infectious or sub-standard product is quarantined and discarded to prevent release to general inventory.

Hoxworth Blood Center no longer performs required donor testing on site. Indiana Blood Center serves as the testing facility for Hoxworth Blood Center and has done so since 2018.

Current Food and Drug Administration (FDA) and AABB required testing, in addition to other supplemental testing is performed to detect/determine:

ABO/Rh

Antibody to

  • Human Immunodeficiency Virus (HIV) Types 1/2, HIV-1 subtypes O and M
  • Hepatitis B Core (HBC) Antigen
  • Human T-Lymphotrophic Virus (HTLV) Types I & II
  • Hepatitis C Virus (HCV)
  • Syphilis (T. pallidum)
  • Chagas Disease (T. cruzi)
  • Red Cell Antigens

Antigen

  • Hepatitis B Virus (HBV) Surface Antigen

Nucleic Acid Testing (NAT) for viral RNA or DNA for

  • HCV
  • HIV
  • HBV
  • West Nile Virus (WNV)

Infectious Disease Testing Information

The Quality Control Laboratory receives many questions concerning the dates of infectious disease testing. The following table is a brief synopsis on the history and current status of infectious disease testing performed at Hoxworth Blood Center.

Infectious Disease Testing Information
INFECTIOUS DISEASE TESTING DATE TEST FIRST IMPLEMENTED CURRENT TESTING IMPLEMENTATION
Hepatitis B Surface Antigen (HBS) Early 1970's Abbott PRISM HBS 9/21/2006
Human Immuno deficiency Virus (HIV) Type 1 Antibody
5/1/1985 Abbott PRISM HIV O Plus (Types 1&2, O, M) 12/1/2009
Hepatitis B Core Antibody (HBC) 7/1/1986 Abbott PRISM HBC 9/21/2006
Alanine Aminotransferase (ALT) Testing 10/14/1986 Discontinued 10/1/2004
Human T-Lymphotrophic Virus (HTLV) Type I Antibody
3/1/1989 Abbott PRISM HTLV Types I/II
4/1/2008
Hepatitis C Virus (HCV) Antibody
5/6/1990 Abbott PRISM HCV 9/11/2007
HIV p24 Antigen Testing by EIA 4/29/1996 Discontinued 6/1/2003
HCV by NAT 4/28/1999

Roche COBAS HIV/HCV/HBV combined in one assay 5/2/11

HIV/HCV NAT combined assay 6/1/2003, discontinued 5/2/11

HIV by NAT 1/3/2000 Roche COBAS HIV/HCV/HBV combined in one assay 5/2/11
HBV by NAT 5/2/11 Roche COBAS HIV/HCV/HBV combined in one assay 5/2/11
West Nile Virus (WNV) by NAT 7/1/2003
(under IND protocol)
Roche COBAS WNV 4/1/2006
Syphilis Antibody
1960's Antibody to T. pallidium in 1/31/1991
Chagas Antibody
12/1/2007 Abbott PRISM Chagas
2/14/2011

EIA = Enzyme Immunoassay

PRISM = Chemiluminescence Immunoassay

NAT = Nucleic Acid Testing

This laboratory performs over 50,000 discrete Quality Control (QC) tests on randomly selected products. By testing randomly selected products, Hoxworth Blood Center is able to ensure that products meet the minimum quality assurance specifications set by the FDA and AABB. The result is that physicians can better manage blood transfusion therapy for their patients knowing that a standard minimum dose is available for transfusion.

Contact Information

Jenine Fields, MT(ASCP)
Manager, Quality Control Laboratory
Phone: (513) 558-1565

Jennifer O’Connor, MSTM, MLS(ASCP)CMSBBCM
Assistant Director, Laboratories
Phone: (513) 558-1549

Judith Gonzalez, BS, MT(ASCP), CLS
Chief Production Officer
Phone: (513) 558-5397

David Oh, MD
Chief Medical Officer
Phone: (513) 558-1338

To contact the Quality Control Laboratory, dial (513) 558-1200. Press 9 for a listing of departments. Press 6 to be connected with the Quality Control Laboratory.

Request or Discuss Donor Test Results

  • Donor test results will only be released to the donor with proper identification.
  • To request a copy of your test results, please contact Donor Services at 513-558-1304.
  • If you have questions or would like to discuss the meaning of a test result, please contact Clinical Services at 513-558-1335.